Moderna与Merck AI辅助个性化mRNA癌症治疗三期试验成功

You guys sure you don’t want more data centers?

精选理由

Moderna和Merck用AI做个性化肿瘤治疗,给病人定方案,效果比单用Keytruda好,去了解下他们的试验结果。

AI 摘要

Moderna和Merck的AI系统为患者分析肿瘤DNA时,成功识别免疫反应靶点,该项目首次通过三期临床试验。此前二期试验显示,接受该治疗的患者五年无癌率68.8%,高于单独用Keytruda的49.1%。此次1137人三期试验也验证疗效优势,推动个性化癌症治疗发展。

原文 · Justine Moore

You guys sure you don’t want more data centers?

You guys sure you don’t want more data centers? Chubby♨️ @kimmonismus This is freaking huge: For the first time, a AI-assisted personalized mRNA cancer treatment has succeeded in a Phase 3 trial. Moderna and Merck sequence each patient’s tumor and compare it with their healthy DNA. AI then helps identify which of the tumor’s mutations are most likely to trigger an immune response. From those targets, Moderna produces an individual mRNA treatment encoding up to 34 neoantigens, The earlier Phase 2 trial followed patients with surgically removed high-risk melanoma for five years: - 68.8% remained cancer-free, compared with 49.1% on Keytruda alone - 49% lower risk of recurrence or death - 59% lower risk of distant metastasis or death Now the much larger Phase 3 trial involving 1,137 patients has also succeeded. Absolutely incredible. Dario was right: cancer will be cured in just a few years! 🔗 View Quoted Tweet 💬 2 🔄 1 ❤️ 17 👀 1339 📊 3 ⚡