#structRFM

The structural-guided pretraining approach shows how language-model techniques transfer to molecular biology, and the model's open-source release lets bioinformatics teams plug its features into existing 3D structure prediction pipelines. Researchers in drug discovery and RNA functional genomics can use it for tasks like splice site prediction without task-specific training. It is also the 16th USTC first-author paper in Nature, Science or Cell so far in 2026, underscoring the pace of Chinese fundamental research.